2007 Program - Detailed

Time

Sunday, February 18

4:30-5:00

Wildrose Centre,

Mezzanine

Poster set-up

5:00–9:00

Wildrose Centre & South, Mezzanine

Registration & Welcome Reception

Registration desk is located outside of elevators on Mezzanine level

6:00

Wildrose Centre & South, Mezzanine

Opening Remarks

Neil Cashman, Scientific Director, PrioNet Canada &Dr. Stephen Moore, Scientific Director, Alberta Prion Research Institute

Welcome Plenary: Florence Kranitz – President, CJD Foundation, Inc.

The Human Side of Prion Diseases, Making a Difference Together

7:00-9:00

Wildrose Centre & South, Mezzanine

Registration & Welcome Reception (continued)

Time

Monday, February 19

7:00-8:00

Mezzanine Foyer, Wildrose North

Breakfast buffet

8:00

Wildrose Centre & South, Mezzanine

8:10

Introduction

Neil Cashman, Scientific Director, PrioNet Canada & Stephen Moore, Scientific Director, Alberta Prion Research Institute

Plenary: Adriano Aguzzi – Director & Chairman, Institute of Neuropathology, UniversityHospitalZurich

Immunology of Prion Diseases

9:00

Wildrose Centre & South, Mezzanine

9:10

9:30

9:50

Creutzfeldt-Jakob Disease Theme Session

Session Chair:Howard Feldman, University of British Columbia

Introduction

Neil Cashman , University of British Columbia

Immunotherapy of CJD

Oral Presentation Award: Angela Catford, University of Guelph

Acoustic Prion Sensor

Guest Speaker: Pierluigi Gambetti, The National CJD Surveillance Centre

Hu man Prion Diseases

10:30 – 11:00

Mezzanine foyer

Break

11:00

Wildrose Centre & South, Mezzanine

11:10

11:30

11:50

Prion Disease Risk Management Theme Session

Session Chair: Maura Ricketts, Public Health Agency of Canada

Introduction

Daniel Krewski , University of Ottawa

Integrated Risk Management Framework for BSE

Josie Smart, University of Calgary and Ellen Goddard, University of Alberta

TSEs and Social-economic Impact in Alberta

Oral Presentation Award: Troy Stozek, University of Manitoba

BSE, Farmers and Towns – Impacts and Adaptations

12:00-1:15

Mezzanine Foyer & Wildrose North 

Lunch buffet

Wildrose Centre & South, Mezzanine

1:15

1:35

Prion Disease Risk Management Theme Session (continued)

Carol Amaratunga, University of Ottawa and Wilfreda Thurston,

University of Calgary

A Cohort Study of the Impact of Prion Disease on Farm Family Community Health

Guest Speaker: Robert Will, University of Edinburgh

Variant CJD: Risk Assessment and Risk Management

2:15

2:20

Bovine Spongiform Encephalopathy Theme Session

Session Chair: Stephen Moore, University of Alberta

Introduction

Stephen Moore, University of Alberta

A Comprehensive and Comparative Approach to Genetics & Pathobiology of Prion Disease

2:40-3:10

Mezzanine foyer

Break

Wildrose Centre & South, Mezzanine

3:10

3:20

3:40

4:00

Bovine Spongiform Encephalopathy Theme Session (continued)

Mike Belosevic, University of Alberta

Prion Inactivation and Environment

Scott Napper, University of Saskatchewan

Immunoprophylaxis of Bovine Spongiform Encephalopathy

Guest Speaker: Ray Bradley, BSE Consultant (UK)

The Rise and Fall of BSE in Europe: And an Introduction to New Members of the Cast

4:40

Closing remarks

Free time

6:30

Wildrose Centre & North, Mezzanine

Dinner Buffet

7:30-9:30

Wildrose Centre & North, Mezzanine

Poster Session

Poster authors participating in the Student & PDF Poster Competition must be present from 7:30-8:30 at their poster for judging. Cash bar will be available.

Tuesday, February 20

7:00-8:00

Mezzanine foyer, Wildrose North

Breakfast buffet

8:00-10:00

Wildrose C,

Mezzanine

Wildrose S,

Mezzanine

Mezzanine

Workshop Sessions

Lab Methods: Jiri Safar, University of California at San Francisco

Conformational Methods of Prion Protein Detection and Strain Discrimination

This workshop will wrap-up with a panel discussion.

Statistics / Epidemiology: Maura Ricketts, Public Health Agency of Canada

Introduction: Michael Tyshenko – Risk Assessment, Precautionary Principle and Use of Scientific Data (5 minutes)

Daniel Krewski – Basic Overview on Statistics and Epidemiology (40 minutes)

Susie ElSaadany – BSE and vCJD Calculation Method for BloodSafety (30 minutes)

Mustafa Al-Zoughool – Use of Back Calculation Method (15 minutes)

David Cottrell – BSE/vCJD Risk Modeling (15 minutes)

Joan Reiter - Overview of the Public Health Agency of Canada (15 minutes)

Science Communications: Jay Ingram, Discovery Channel Canada

Effective Science Communications

Through some examples from the group, Jay will walk through tools and techniques for effectively translating science for engaging and understandable information for public and media.

10:00-10:30

Mezzanine foyer

Break

10:30

Wildrose Centre & South, Mezzanine

10:50

11:10

11:30

Prion Protein Structure and Function Theme Session

Session Chair: David Westaway, University of Alberta

Introduction

Joel Watts, University of Toronto

Properties of the Shadoo Protein

Avi Chakrabartty, University of Toronto

Structure Elucidation of Antibody: Prion Protein Complexes

John Glover, University of Toronto

The PrP Interactome: Toward a Comprehensive Compendium of PrP Interacting Proteins

Guest Speaker: Jiri Safar, University of California at San Francisco

Prion Clearance and Plasma lipoproteins

12:00-1:00

Mezzanine Foyer & Wildrose North 

Lunch buffet

Wildrose Centre & South, Mezzanine

1:00

1:20

1:40

2:00

2:15

2:30

2:40

Prion Protein Structure and Function (continued)

Xavier Roucou, University of Sherbrooke

Pathobiology of Prion Protein Aggregates: Mechanism of Propagation and Toxicity of Aggregates Produced in the Cytoplasm

David Wishart, University of Alberta

A Novel Approach to Characterize Prion Aggregates and the Prion Propagation Complex

Shoshana Wodak, Hospital for Sick Children

Mechanism of Domain-swapped Oligomer Formation of Prion Proteins

Charles Holmes, University of Alberta

Molecular Characterization of a Novel Prion Protein Signal Transduction Pathway

Brian Sykes, University of Alberta

Prions: A Structural View 

Oral Presentation Award: Kevin Goggin, University of Sherbrooke

Clustering of mRNAs in Prion Aggresomes Prevents the Assembly of Stress Granules

Guest Speaker: George Carlson, McLaughlin Research Institute

Host Responses to Prion Infection: A Systems Approach to Prion Replication and Pathogenesis

3:10-3:30

Mezzanine foyer

Break

3:30

Wildrose Centre & South, Mezzanine

3:40

4:00

4:20

4:30

4:40

4:55

Chronic Wasting Disease Theme Session

Session Chair: Ted Leighton, Canadian Cooperative Wildlife Health Centre

Introduction

Trent Bollinger, University of Saskatchewan

Factors Affecting the Spread of CWD in Wild Deer

David Coltman , University of Alberta

Proactive Surveillance & Management of Chronic Wasting Disease in Alberta's Wild Cervid Populations

Oral Presentation Award: Gregory Wilson, University of Alberta

The Use of Landscape Genetic Techniques to Estimate CWD Spread in Alberta and Saskatchewan

Stephen Moore, University of Alberta

A Comparative Approach Examining Host Response to TSE Infection by Serial Analysis of Gene Expression (microSAGE) in Cervids and Ovids

Christoph Sensen, University of Calgary
Preliminary Characterization of Chronic Wasting Disease in Elk

Guest Speaker: Michael Samuel, Wisconsin Cooperative Wildlife Research Unit

CWD in Wisconsin: Lessons Learned

5:30

Closing Remarks

6:00-7:00

Mezzanine Foyer

Networking Reception

7:00-9:00

Banquet Dinner - Poster Awards Presentation and Closing Remarks

Dr. Neil Cashman, Scientific Director, PrioNet Canada & Dr. Peter Hackett, President, Alberta Ingenuity Fund

Closing Plenary: Dr. Robert Church, Professor Emeritus, University of Calgary and Chair Emeritus, Alberta Science and Research Authority             

7:30-8:30

Mezzanine foyer, Wildrose North

8:30–10:00

PrioNet and APRI members:
Research Theme Break-out Sessions

BSE: Glacier Lily
CWD: Calypso
CJD: Primrose
Structure & Function: Wildrose C
Risk Management: Willow

10:00-10:30

Break