2008 Program
SUNDAY, FEBRUARY 3
4:00–5:00 Exhibitor Set-up
4:30-5:00 Poster Set-up
5:00-9:00 Registration and Welcome Reception
6:00-6:45 Welcome Remarks: Neil Cashman, PrioNet Canada and Stephen Moore, Alberta Prion Research Institute
Welcome Address: Suzanne Fortier - President, The Natural Sciences and Engineering Research Council
MONDAY, FEBRUARY 4
7:00-8:00 Breakfast buffet
8:00-9:00 Introduction: Neil Cashman, PrioNet Canada, and Stephen Moore, Alberta Prion Research Institute
Plenary: Byron Caughey - Laboratory of Persistent Viral Diseases, NIH/NIAID Rocky Mountain Laboratories
"Prion protein oligomerization and TSE disease"
9:00-11:30 Theme Session: Infectivity and Transmission
Guest Speaker: Glen Telling - University of Kentucky Medical Center
"Transgenetic and in vitro modeling of interspecies prion transmission barriers"
Research Presentations:
• Trent Bollinger - Western College of Veterinary Medicine, University of Saskatchewan and David Coltman, Ecology/Faculty of Science, University of Alberta
"Factors affecting prevalence and geographic spread of chronic wasting disease in wild deer in Saskatchewan and Alberta"
• Stephen Moore - Beef Genomics Initiative, Faculty of Agriculture, University of Alberta
"The genetics of BSE, genetic variation and gene expression profiling approaches to understanding the pathobiology of disease"
• Highly Qualified Personnel Awardee: Qasim Khan - University of Toronto
"Thermodynamic Stability of an Oligomeric PrP Folding Intermediate as a Determinant of Prion Disease Susceptibility"
11:35-2:00 Poster Session and Buffet Lunch
12:00-1:00 Lunch
1:00 Guided Poster Tour
1:30 Guided Poster Tour
2:00-3:30 Theme Session: Population and Risk Assessment
Guest Speaker: Linda Detwiler - Virginia-Maryland Regional College of Veterinary Medicine, University of Maryland
Research Presentations:
• Ellen Goddard - Agricultural Marketing and Business, Faculty of Agriculture, University of Alberta
"Socioeconomic impacts of TSEs"
• Daniel Krewski - R. Samuel McLaughlin Centre for Population Health Risk Assessment, University of Ottawa
"An integrated risk management framework for BSE in Canada"
• Highly Qualified Personnel Awardees:
Mustafa Al-Zoughool - University of Ottawa
"Combining Quantitative Models for BSE and vCJD: Developing an Accessible Tool for Prion Disease Risk Analysis in Canada"
Jun Yang - University of Alberta
"How Media Information Affects Canadian Consumers’ Risk Perceptions on BSE and Rally Behaviour for Canadian Beef Cattle Farmers"
4:00-5:30 Concurrent Workshops (choice of three):
I) An Introduction to Intellectual Property; Start-up Funding (IDeal
and Bootstrap)
David Barran and Lesley Rappaport, Borden Ladner Gervais
II) Tips and Tricks for Working with Media
John Crean - NATIONAL Public Relations
III) Effective Granting Writing – What You Should Know
Nadine Cyr - Alberta Ingenuity
5:30-7:00 Prion Institute and PrioNet Member Break-out Session
TUESDAY, FEBRUARY 5
7:00-8:00 Breakfast buffet
8:00-9:00 Plenary Presentation: Jay Ingram - Discovery Channel Canada
9:00-11:30 Theme Session: Preventative Therapies and Potential Treatments
Guest Speaker: Yongzhang Luo - Laboratory of Protein Chemistry, Department of Biological Sciences & Biotechnology, Tsinghua University
"Protein Misfolding and Discovery of a New Extracellular Chaperone"
Research Presentations:
• Neil Cashman - Brain Research Centre, University of British Columbia
"PrPSc exposure of TYR-TYR-ARG: marker, probe, and treatment target"
• Nat Kav - Biochemistry, Biotechnology, and Functional Genomics, Faculty of Agriculture, University of Alberta
"Characterization of a prion protein-specific recombinant antibody"
• Scott Napper - Vaccine and Infectious Diseases Organization, University of Saskatchewan
"Immunoprophylaxis and therapy of Bovine Spongiform Encephalopathy"
11:30-12:15 Concurrent Panels (choice of one):
I) Is BSE yesterday's problem?
II) PrP - One trick pony or poster child?
12:15-2:15 Poster Session and Buffet Lunch
12:15-1:15 Lunch
1:15 Guided Poster Tour
2:15-5:15 Theme Session: Protein Folding and Misfolding
Guest Speaker I: Judd Aiken - School of Veterinary Medicine, University of Wisconsin
Guest Speaker II: Joaquin Castilla - The Scripps Reseach Institute
"Replication of prions in a cell-free system"
Research Presentations:
• Xavier Roucou - Biochemistry, Faculty of Medicine, University of Sherbrooke
"Mistrafficking of PrP in the cytoplasm induces the mistrafficking of RNA molecules"
• David Westaway - The Centre for Prion and Protein Folding Diseases, University of Alberta
"Paired Activity and Variation of PrPC and Shadoo"
• Shoshana Wodak - Hospital for Sick Children (Toronto)
"Mechanism of domain-swapped oligomer formation of prion proteins"
• Highly Qualified Personnel Awardee: Bela Reiz - Unversity of Alberta
"Microwave-Assisted Acid and Base Hydrolysis Combined with MALDI-MS for the Study of Prions"
5:15 Wrap-up
6:00-7:00 Networking Reception
7:00-9:00 Banquet Dinner
Highly Qualified Personnel Oral Awards Presentation
Student and Post-doctoral Fellow Poster Awards Presentation
Closing Keynote: Dr. Stephen Morgan Jones - Director General, Sustainable Production Systems, Agriculture and Agri-Food Canada
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