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MONDAY, March 8
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5:00-9:00
Confederation II
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Poster set-up
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5:00-6:00
Nunavut
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Registration
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5:00-6:00
Quebec Room
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Prion 101
Scott Napper, Vaccine and Infectious Disease Organization / University of Saskatchewan
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5:00–9:00
Nunavut and Governor General Ballroom
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Registration and Welcome Reception
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6:30-6:40
Governor General Ballroom
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Welcome Remarks:
Neil Cashman, PrioNet Canada, and Kevin Keough, Alberta Prion Research Institute
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6:40-7:00
Governor General Ballroom
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Welcome Address
Tom Brzustowski, RBC Professor for the Commercialization of Innovation, University of Ottawa and Chair of the Board, Institute for Quantum Computing, University of Waterloo
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TUESDAY, MARCH 9
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7:30-8:30
Confederation III
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Breakfast buffet
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8:30-8:40
Confederation I
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Introduction:
Kevin Keough, Alberta Prion Research Institute
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8:40-9:10
Confederation I
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Guest Speaker
BSE in Canada: risk factors and control measures
Noel Murray, Canadian Food Inspection Agency
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9:10-12:00
Confederation I
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Theme Session - Social and Field Sciences
Session Chair: Ted Bilyea, Ted Bilyea and Associates
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9:10-9:30
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The impact of BSE policy responses on animal management and food safety in Alberta
Josephine Smart, University of Calgary
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9:30-9:50
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Managing the Psychosocial Risk of Prion: Anticipation, Perception, Communication
Louise Lemyre, University of Ottawa
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9:50-10:20
Confederation II
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Break
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10:20-10:40
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Innovative KTSE in relation to Risk management TSE's: STRUCTURED EXPERT ELICITATION
Susie ElSaadany, Public Health Agency of Canada
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10:40-10:55
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Highly Qualified Personnel Oral Presentation Award:
Landscape structure and deer distribution: Implications for contact rates and CWD
Tom Habib, University of Alberta
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10:55-11:15
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Canadian Public Awareness of and Concerns About Chronic Wasting Disease
Ellen Goddard, University of Alberta
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11:15-11:30
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Highly Qualified Personnel Oral Presentation Award:
Predicting the spread of chronic wasting disease in east central Alberta using deer movement models
Barry Nobert, University of Alberta
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11:30-12:00
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Guest Speaker
Update on diagnosis and treatment of CJD
Michael Geschwind, University of California – San Francisco, Memory and Aging Center
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12:00-1:00
Confederation III
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Lunch
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1:00-2:00
Confederation II
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Poster Session
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2:00-3:30
Governor General I
Confederation I
Provinces I
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Concurrent Workshops
1)
Communications – New Media
Blogging? Tweeting? Podcasting? What do these all mean? Learn how these free, easy to learn communications and new media tools can assist your research endeavours and inform society.
Colin Anderson, University of Manitoba
Stéphane
McLachlan, University of Manitoba
Valerie Sim, University of Alberta
Mike Spear, Genome Alberta
2) Basics of Molecular Dynamics Simulations
This workshop introduces the fundamental principles of molecular dynamics (MD) simulations, to illustrate how an MD simulation of a protein system is performed, and to discuss the role of such simulations in prion research.
Anatoly Malevanets and Stephen MacKinnon,
Wodak Lab, Hospital for Sick Children
3) Public Policy
This session provides an overview of how the government functions related to policy development, and overall, the role of science and research and its impact on policy decision making.
Jeff Kinder, Natural Resources Council
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3:30-3:50
Confederation II
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Break
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3:50-5:30
Confederation I
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Theme Session – Structure and Chemistry
Session Chair: Bob Hills, Health Canada
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3:50-4:10
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A novel coding mutation in human PRNP and its potential implications for protein structure
Michael Coulthart, Public Health Agency of Canada
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4:10-4:25
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Highly Qualified Personnel Oral Presentation Award:
pH Induced Structural Changes and Fibrilar formation of the Syrian Hamster Prion Protein (shPrP)
Trent Bjorndahl, University of Alberta
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4:25-4:45
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Comparative Proteomics: Searching for Surrogate Markers
David Knox, Public Health Agency of Canada
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4:45-5:00
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Highly Qualified Personnel Oral Presentation Award:
Single molecule investigation of prion protein structural transitions important in disease
Nahid Jetha, University of British Columbia
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5:00-5:20
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Characterization of local structural stability in PrP molecules by numerical analysis of coarse-grained conformational dynamics
Maria Stepanova, National Institute for Nanotechnology, NRC
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5:20
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Wrap-up
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WEDNESDAY, MARCH 10
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7:30-8:30
Confederation III
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Breakfast buffet
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8:30-8:40
Confederation I
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Introduction:
Neil Cashman, PrioNet Canada
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8:40-9:10
Confederation I
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Guest Speaker
Prion generation, characterization, and detection by seeded conversion of recombinant PrP
Byron Caughey, NIAID Rocky Mountain Laboratories, National Institutes of Health
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9:10-10:30
Confederation I
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Theme Session – Biology
Session Chair:
Antanas Staskevicius, University of Sherbrooke
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9:10-9:30
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Exploring the PrP interactome using zebrafish genetics
Ted Allison, University of Alberta
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9:30-9:50
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The role of the glycine rich region of PrP in prion infection
Andrew Hill, University of Melbourne
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9:50-10:05
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Highly Qualified Personnel Oral Presentation Award:
Role of nicotinic acetylcholine receptor on intracellular calcium signaling mediated by the cellular prion protein
Flavio Beraldo, University of Western Ontario
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10:05-10:30
Confederation II
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Break
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10:30-12:00
Confederation II
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Poster Session
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12:00-1:00
Confederation III
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Lunch
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1:00-2:15
Confederation I
Provinces I
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Panels
1)
Adapting to Chronic Wasting Disease: present and future implications
Moderator: Frederick Leighton, Canadian Cooperative Wildlife Health Centre
Vic Adamowicz, University of Alberta
Daniel Krewski, University of Ottawa
Stéphane McLachlan, University of Manitoba
2)
PrP in disease – is it a gain or loss of function?
Moderator: Neil Cashman, University of British Columbia
Jan Braun, University of Calgary
Marco Prado, University of Western Ontario
Luis Schang, University of Alberta
David Westaway, University of Alberta
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2:20-5:30
Confederation I
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Theme Session – Biology (continued)
Session Chair: Ted Allison, University of Alberta
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2:20-2:40
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Upregulation of miRNAs in the brain of BSE-infected macaques
Dirk Motzkus, German Primate Centre
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2:40-3:00
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The ironic role of iron in prion disorders
Neena Singh, Case Western Reserve University
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3:00-3:30
Confederation II
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Break
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3:30-3:50
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Prion-like propagation of SOD1 misfolding in vitro
Neil Cashman, University of Alberta
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3:50-4:10
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Design and Delivery of a Cryptic PrPC Epitope for Induction of PrPSc-Specific Antibody Responses
Scott Napper, Vaccine and Infectious Disease Organization
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4:10-4:25
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Highly Qualified Personnel Oral Presentation Award:
Prion protein interaction with Stress-inducible protein 1 enhances neuronal protein synthesis through an mTOR pathway
Glaucia Hajj, Ludwig Institute for Cancer Research
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4:25-4:40
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Highly Qualified Personnel Oral Presentation Award:
Cryptic out-of-frame initiation of human PrP mRNA produces a novel 9 kDa polypeptide
Antanas Staskevicius, University of Sherbrooke
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4:40-5:00
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Gene Expression Profiling in BSE-infected Cattle
Otto Windl, Veterinary Laboratories Agency
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5:00
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Wrap-up
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6:00-7:00
Foyer
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Networking Reception
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7:00-9:00
Confederation I
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Banquet Dinner and Student and Post-doctoral Fellow Poster Awards Presentation
Closing Address:
Healthy Individuals, Healthy Communities, Healthy Societies: the increasing role of the social sciences and humanities
Chad Gaffield, President, Social Sciences and Humanities Research Council
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